Florfenicol Sodium Succinate
Zita rezvigadzirwa: Florfenicol sodium succinate

Chemical zvivakwa:
Ichena kana chena-yakafanana nekristaro poda, isina odhita uye isina kunaka, kana mweya wekunyorova yakakwirira kuburquecent Ichi chigadzirwa chinogadziriswa zvishoma muacetone, ethanol, iri nyore kunyungudika mumvura, ine florfenicol sodium muyanteri haisi pasi pe95%.

Chigadzirwa Feature:
1. Florfenicol sodium inogonesa inogadzira iyo Florfenicol solubility kusvika 300mg / ml uye yakawedzera makumi mana.
2. Florfenicol sodium inogonesa inoita iyo yeFlorfenicol muyero wekuparadza mazana mazana maviri nekukurumidza, pasina chero co-solvent, soluble papo mumvura.
3. Florfenicol sodium preserate ndeyeFlorfenicol inobuda, ichipinda mumuviri neiye enzyme yakanyatsoiswa mukati meflorfenicol uye inobudirira yeropa kusimuka kwenguva yakareba.
4. Hazvitsvage kutora chikamu cheganiki chinogona kushandiswa mukutarisira kiriniki, kudzivirira mhedzisiro yekushandisa iyo organic solvent (kuvandudza kuchengetedzwa kwemushonga, kuderedza zvakasara).

Pharmacology:
Ichi chigadzirwa ndecheFlorfenicol derivatives, zvinoenderana nesimboti yeyakagadzirwa dhizaini yakaita kuti ive dzakasiyana-siyana dzegiramu-yakanaka uye gramu-isina hutachiona uye ine chinzvimbo mune mycoplasma.
Iyo antibacterial mechanism iri neiyo 50S ribosomal subunit, uye inhibits kiyi enzyme inodikanwa yeprotein synthesis - iyo peptidyl transferase, iyo yaizonyatso dzivirira iyo aminoacyl-tRNA inosunga kune receptors pane ribosome inhibitory peptide keteni yakawedzerwa ichisiya protein yehutachiona haigone kuvezwa . Ichi chigadzirwa hachizongori chete charo-chinogadziriswa chemvura, uye nemuromo uye jekiseni muitiro we-vivo kurasikirwa, mushure me enzyme metabolism mumuviri kuora mukati meesters uye florfenicol ester kukunda bhakitiriya kuramba. Florfenicol inotarisa, tamba zvinodhaka zvinoshanda zvakanyanya kuita pane chisikwa, huwandu hwacho hushoma, hunokurumidza kuita, hupenyu hwakareba, hupenyu hweplasma yakawandisa, nguva yakareba yekuchengetedza plasma. Kunyanya neitsvo excretion.
 
Zviratidzo
Inoshandiswa muhuku E. coli chirwere uye Serositis nehove inouraya salmon Aeromonas, Vibrio svutugadzike yemabhakitiriya anotyisa mumombe, nguruve, huku hutachiona hwehuku uye mycoplasma inokonzerwa nekurapa kwekufema.
 
Dosi
Kuku: chakasanganiswa chinwiwa che 100L mvura 3.5-4g, zvipfuyo, pahupfu hwehuremu hwemuviri 20-25mg, kamwe pazuva uye shandisa mazuva matatu. IM: huku, nguruve, mombe uye huwandu hwenguva kilogiramu yehuremu hwemuviri we 15-20mg, yega 48h panguva. shandisa kaviri.